The Tokyo Series jumpstarted MLB's 2025 regular season schedule on March 18-19, with the defending World Series champion Dodgers earning a two-game sweep over the Cubs at the Tokyo Dome. But that was just a sneak preview of sorts.

The wait is over, Opening Day is finally here, and with it comes a stacked slate of electrifying pitching duels. From CY Young winners to fireballing young hurlers, some of baseball’s best arms will go toe to toe in what promises to be an exciting start to the MLB season.

After a long, cold winter, the MLB season is now fully underway. Here's every MLB Opening Day game, start time, matchup and storyline.

On Opening Day eve, the Yankees made one last bullpen decision Wednesday by picking left-hander Brent Headrick and rookie right-hander Yoendrys Gomez over veteran righty Yerry De Los Santos to be part of their 26-man season-opening roster.

Austin Wells, the team's starting catcher, will lead off on Opening Day against the Milwaukee Brewers at Yankee Stadium -- a first in the team's history.

The Houston Astros will carry prospect Cam Smith on their opening day roster, team officials said Tuesday, culminating a rapid ascent by the 22-year-old to the majors. Smith, acquired by the Astros in their trade of Kyle Tucker to the Cubs,

Now, call Cam Smith a major leaguer. Smith made the Houston Astros’ Opening Day roster, three league sources told The Athletic on Tuesday, completing his six-week captivation of an entire coaching staff and clubhouse.