Getting him signed is a big score for the 49ers front office.

Not many seasons for the San Francisco 49ers have come and gone over recent years without the existence of significant ...

The San Francisco 49ers have signed CB Nick McCloud and released S Adrian Amos from the team’s practice squad.

Following a lengthy holdout during training camp, Brandon Aiyuk signed a four-year, $120 million contract with the San Francisco 49ers in late August. After landing his new deal, Aiyuk and the 49ers ...

Fantasy football analyst Matt Harmon examines some of the biggest storylines coming out of Week 10's Sunday action.

San Francisco QB Brock Purdy connected with the rookie, who missed the team's first six games after being shot during an ...

Welcome to the NFL, Ricky Pearsall. The 49ers' No. 31 overall pick from this year's draft didn't make it onto the field until ...

Christian McCaffrey is set to make his season debut for the San Francisco against the Tampa Bay Buccaneers on Sunday. How ...

The Sunday primetime matchup between the Cowboys and 49ers at Levi’s Stadium will air on NBC and stream on Peacock. One of the NFC's oldest rivalries closes out Sunday's action in Week 8 of the ...

It's not usually a tough call to start a quarterback facing the Jaguars poor defense. Darnold has played well enough this season and this will likely be a nice spike week, especially with T.J.

With the stretch run of the NFL season looming, ESPN released a flurry of midseason predictions for multiple teams, including ...