Sure enough, SGLT2 inhibition with canagliflozin significantly reduced the previously elevated number of PD-L1-positive senescent cells in HFD-fed mice. Conversely, suppression of immune cells ...

Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, ...

The virus takes control of three key host proteins that suppress the activity of the complement system. Researchers at the ...

The discovery offers insight into why shift workers experience metabolic disruption, which could lead to new therapies for managing obesity and preventing muscle wasting. Recent research shows that ...

Renal glucose reabsorption involves two transporter families: the SGLTs secondary active Na + /D-glucose co-transporters located at the brush border of tubular cells (SGLT2 and SGLT1) and the ...

These miniature immune system models -- known as human immune organoids -- mimic the real-life environment where immune cells learn to recognize and attack harmful invaders and respond to vaccines.

The new technique could kill a wide range of cancer cells, including breast and prostate A newly-discovered part of our immune system could be harnessed to treat all cancers, say scientists.

Prof. Fabry emphasizes, "Our discovery that immune cells can create high contraction forces for a brief period of time is only one example of how this new method will lead to fundamental discoveries.

Researchers Make Glioblastoma Cells Visible to Attacking Immune Cells Nov. 7, 2024 — Researchers have identified a possible way to make glioblastoma cells vulnerable to different types of ...

Of note, a similar proportion of patients in the empagliflozin and placebo groups (43% and 40%, respectively) were using an SGLT2 inhibitor during the post-trial period, they wrote in the New ...

Researchers at Winship Cancer Institute of Emory University have identified a novel type of immune cell, called the stem-like ...

The brain, traditionally considered an immune-privileged organ due to the blood-brain barrier (BBB), has its own sophisticated immune defense system. Microglia, the primary immune cells of the central ...