Judges declare the 2020 conviction of the former NFL Defensive Player of the Year is ‘legally invalid’ after finding his race ...

San Francisco 49ers top scorers look to capitalize on opportunities early against Detroit Lions stout defense.

San Francisco 49ers face a daunting Week 17 test against Detroit Lions with injuries threatening their ability to compete.

The San Francisco 49ers face slim odds of landing a top-nine pick in the 2025 NFL Draft. The Carolina Panthers and New York ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

The Miami Dolphins inched closer to finishing their season with a winning record by beating the San Francisco 49ers a week ...

For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

A California appeals court has overturned the rape conviction of former San Francisco 49er Dana Stubblefield after ...

Nick Bosa and a San Francisco 49ers teammate spoke about playing for "Integrity" after NFL playoff elimination.

San Francisco 49ers tight end George Kittle has recorded three games with at least 100 receiving yards this season, the most ...

Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking up the no. 1 seed.

BYU AD Tom Holmoe was once Deion Sanders’ position coach with the 49ers. Thirty years later, the two will meet again in the ...