Production tips from Crystal Bio, TriLink Biotechnologies, Ginkgo Bioworks, Quantoom Biosciences, and Parexel.

Nanoparticles have once again reached the spotlight, this time as a critical tool to combat the spread of covid-19. In this ...

At its so-called 3' end, mRNA is equipped with a polyadenine tail with an average length of 200 nucleotides. But even this ...

Crispr has already secured a historic first approval for a CRISPR/Cas9 drug and has several more potential blockbuster ...

The mRNAs are formulated in novel patented lipid nanoparticles, which prolong the half-life of the mRNA and deliver it to immunoactive antigen-presenting cells, which enhances T-cell responses.

Discover how next-generation "switchable" CAR-T cells could improve both the safety and efficacy of CAR-T therapies.

It performs two main functions: first, it extends effective half-life of LNPs in the bloodstream by diminishing ... the progress of improvements in LNP-based systems of delivery of mRNA owing to ...

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This project has not set up a SECURITY.md file yet.

difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust ...

difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust ...

However, production of the mRNA used in vaccines is hindered by its production, which involves both chemical synthesis and a slower enzyme-mediated process. A team of researchers has successfully ...