Kyle Shanahan sits down with Greg Papa on "49ers Game Plan" to break San Francisco's upcoming matchup with the Detroit Lions ...

Nolan Bianchi, John Niyo, Richard Silva and Bob Wojnowski of The Detroit News offer predictions for Monday's Lions-49ers game ...

On Monday, the Lions and 49ers will meet in a rematch of last season’s NFC title game at Levi’s Stadium. After holding a ...

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Spencer Burford officially has been ruled out of San Francisco's Week 17 game against the Detroit Lions on Monday night at ...

Coach Dan Campbell stood at the podium after Detroit blew a 17-point lead to San Francisco in last season's NFC title game ...

To make matters worse, offensive lineman Spencer Burford, who was supposed to start at left tackle with Williams and his ...

For Lions defensive coordinator Aaron Glenn's money, 49ers star George Kittle is the best tight end in football.

Last time the 49ers faced Detroit, they won but also gave up 31 points. And that was in the NFC Championship Game last season ...

David Montgomery (knee) is the only player missing from the active roster. The starting running back remains in limbo, with ...

San Francisco 49ers running back Isaac Guerendo is expected to play Monday night against the Detroit Lions, according to ESPN ...

Detroit Lions defensive coordinator Aaron Glenn called San Francisco 49ers TE George Kittle 'the best tight end in the game.' ...