Temperatures will plummet by up to 40 degrees this weekend as an arctic blast spreads across much of the U.S., including the Deep South.

A potent shot of Arctic air starts settling in Monday as a massive dip in the jet stream pulls in frigid air across the entire eastern half of the country. Temperatures are set to drop as low as 20 degrees below average Tuesday and Wednesday with highs only reaching the teens, with lows in the single digits and even plunging below zero.

An arctic blast will send temperatures across the United States plummeting as bitterly cold air that originated in Siberia will arrive from Canada by week’s end, bringing with it dangerously cold wind chills for millions of Americans.