In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...

For DNA to replicate, the helix must first unwind and break the DNA from a double strand into two single strands. Upon binding, helicases melt the DNA, breaking the chemicals bonds holding the ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.

Heavy-ion therapy, one of the most advanced radiotherapy techniques, has proven to be more effective than conventional X-rays ...

The goal of genome editing technology is to develop strategies for the correction of those mutations that are responsible of ...

"The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells," said Dr ...

Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

In addition to Lander and Zerio, authors of the study, “Human polymerase θ helicase positions DNA microhomologies for double-strand break repair,” include Yonghong Bai, Brian A. Sosa-Alvarado ...

A recent study has made significant progress in uncovering the microscopic mechanism behind heavy-ion cancer therapy.