A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical ...

Proteins are long molecules that must fold into complex three-dimensional structures to perform their cellular functions.

A new study reveals a possible protein misfolding mechanism that may resolve a long-standing mystery of why certain proteins ...

University of Illinois at Urbana-Champaign researchers have developed a CRISPR-based diagnostic tool capable of detecting ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

We develop mathematical models of ctDNA kinetics driven by tumor response to several therapy classes and use them to simulate randomized virtual patient cohorts to test candidate biomarkers. Using ...

Optimizations in reaction temperature (33°C), steric hindrance strategies, and enzyme kinetics improved specificity and reduced nonspecific signal interference. In testing, the assay successfully ...

Mar. 11, 2025 — An innovative new technique uses a novel DNA barcode system to track hundreds of RNA and protein molecules in single cells within thick biological samples, providing researchers ...

The Fund seeks long-term growth of capital by investing in U.S. and foreign equity stocks including common stock, preferred stock, securities convertible into common stock, warrants, rights and ...

Marine biology is the study of life in the oceans and brackish waters, which ranges from archaea and bacteria to marine mammals, and includes organisms such as corals that affect the shape of the ...