A figure estimates that 90% of genetic variants associated with the production of fetal hemoglobin in sickle cell disease (SCD) patients of African ancestry are known, a key finding of the ...

On this map, the distribution of sickle-cell anemia haplotypes among nations with ... The haplotype data represented in this image were summarized from genetic epidemiological studies of sickle ...

A brain image from a healthy individual (left) shows a larger brain with more white matter ... Genetic Carriers for Sickle Cell Disease Have Higher Risks of Blood Clots Across Diverse Ancestries ...

The cells' sickle shape and associated fragility result in rapid RBC destruction by a patient's own body. This leads to leads to anemia, as well as congestion and fibrosis of the spleen at an ...