Medically reviewed by Jane Kim, MD Early signs of sepsis may include severe pain, shortness of breath, and mental confusion.

known as the Severe Sepsis/Septic Shock Management Bundle (SEP-1). Sepsis, a life-threatening condition arising from ...

Purpose. The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. Summary. The medical literature was ...

SEP-1 was adopted based on evidence that bundle compliance was associated with lower mortality rates. In 2023, CMS announced ...

In the past two months, two studies have found little to no association between CMS’ sepsis care rule and improved mortality.

Sepsis is a serious condition that can become life-threatening if not treated quickly. It happens when the body reacts to an ...

The following is a summary of “Epidemiology of sepsis-associated acute kidney injury in the ICU with contemporary consensus ...

Of 12 observational studies in their systematic review that addressed the relationship between mortality and compliance to the Severe Sepsis and Septic Shock: Management Bundle (SEP-1), five ...

Sepsis occurs when bacteria enter the bloodstream, often from another infection, and can be life-threatening. Heart valve and organ damage are possible and may lead to septic shock. Septic shock ...

Sepsis is dangerous, particularly when it isn't treated early, and it can lead to the even more deadly condition of septic shock -- a massive drop in blood pressure that can quickly damage organs ...