This condition is called sepsis. Although sepsis advances through several stages, its last stage, septic shock, can be fatal.

Medically reviewed by Jane Kim, MD Early signs of sepsis may include severe pain, shortness of breath, and mental confusion.

The immune system typically can ramp up the body's defenses to clear out an invading threat without issue. Glitches can ...

The phase 2 AdrenOSS-2 trial has demonstrated the benefits of this biomarker-guided approach. In AdrenOSS-2, which recruited 301 patients across 24 active European sites, septic shock patients ...

Despite persistent racial and ethnic disparities in postoperative sepsis and septic shock risk, there is no evidence of inequity in regard to failure-to-rescue (FTR) rates for either condition. These ...

Purpose. The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. Summary. The medical literature was ...

The Tigris Trial is a confirmatory study of PMX in addition to standard care vs standard care alone and is designed as a 2:1 randomized trial of 150 patients using Bayesian statistics. Endotoxic ...