This condition is called sepsis. Although sepsis advances through several stages, its last stage, septic shock, can be fatal.

The immune system typically can ramp up the body's defenses to clear out an invading threat without issue. Glitches can ...

Severe sepsis and septic shock are progressive stages of sepsis, associated with multi-organ failure and death. According to WHO, there were an estimated 49 million sepsis cases and 11 million ...

Despite persistent racial and ethnic disparities in postoperative sepsis and septic shock risk, there is no evidence of inequity in regard to failure-to-rescue (FTR) rates for either condition. These ...

The phase 2 AdrenOSS-2 trial has demonstrated the benefits of this biomarker-guided approach. In AdrenOSS-2, which recruited 301 patients across 24 active European sites, septic shock patients ...

Purpose. The efficacy and safety of granulocyte colony-stimulating factor (G-CSF) in critically ill patients with severe sepsis or septic shock were evaluated. Summary. The medical literature was ...

The Tigris Trial is a confirmatory study of PMX in addition to standard care vs standard care alone and is designed as a 2:1 randomized trial of 150 patients using Bayesian statistics. Endotoxic ...