We develop mathematical models of ctDNA kinetics arising from tumor cell population responses to targeted therapy, chemotherapy, and radiotherapy and examine how these mechanisms drive distinct ...

A differentiable variant of the Gillespie algorithm enables gradient-based optimization for stochastic chemical kinetics, facilitating efficient parameter estimation and the design of biochemical ...

Yet, this is the goal of biology at the molecular level — to understand the collaborative functioning of the elements as being part of a system that forms a cell, a tissue, even an organism.

The system combines non-perturbing cell visualization and data acquisition with integrated analysis to provide kinetic insights about mechanism of action and other effects. Antibody-drug conjugates ...

BioSpa 8 can automate your workflows, from ELISA to long term live cell assays. Temperature and CO2/O2 control, plus humidity monitoring and lid handling ensure an ideal environment for cell cultures ...

Modern biology generates large datasets on ... integrating and making sense of these datasets to understand cell metabolism ...