Scientists have provided the most detailed account yet of the earliest stages of DNA replication, an essential process for ...
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In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solvedIn a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...
The goal of genome editing technology is to develop strategies for the correction of those mutations that are responsible of ...
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Research by UMass Chan scientists upends scientific understanding of how anticancer drugs kill cancer“The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells,” said Dr.
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Heavy-ion therapy, one of the most advanced radiotherapy techniques, has proven to be more effective than conventional X-rays ...
For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.
Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...
"The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells," said Dr ...
In addition to Lander and Zerio, authors of the study, “Human polymerase θ helicase positions DNA microhomologies for double-strand break repair,” include Yonghong Bai, Brian A. Sosa-Alvarado ...
A recent study has made significant progress in uncovering the microscopic mechanism behind heavy-ion cancer therapy.
Heavy-ion therapy, one of the most advanced radiotherapy techniques, has proven to be more effective than conventional X-rays ...
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