A double-strand DNA break (DSB) occurs or arises when both strands of the DNA duplex are severed, often as the result of ionizing radiation. They are particularly deleterious as the DNA ends can ...

In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks (DSBs) formation. Meiosis, a specialized form of cell division in most ...

For the first time, scientists have witnessed the very moment DNA begins to unravel, revealing a necessary molecular event for DNA to be the molecule that codes all life.

Heavy-ion therapy, one of the most advanced radiotherapy techniques, has proven to be more effective than conventional X-rays ...

For DNA to replicate, the helix must first unwind and break the DNA from a double strand into two single strands. Upon binding, helicases melt the DNA, breaking the chemicals bonds holding the ...

“The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells,” said Dr.

A recent study has made significant progress in uncovering the microscopic mechanism behind heavy-ion cancer therapy.

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

"The conventional thinking has been that single-stranded DNA breaks from PARPi ultimately generated DNA double-strand breaks, and that was what was killing the BRCA mutant cancer cells," said Dr ...

Boosting cells with a tardigrade protein reduced DNA damage after radiation, offering potential protection for healthy tissue ...

Heavy-ion therapy, one of the most advanced radiotherapy techniques, has proven to be more effective than conventional X-rays ...