Serifopoula is a Greek island in the Cyclades. It is a part of the municipality of Serifos. Serifopoula was uninhabited at the 2001 Greek census. The island is largely barren of vegetation, and consists of a large main island 1.36 square kilometres in size, and a small rock, separated by a small 19 metres strait to the island's east, 5,130 square metres in size.