Charlotte is a city in Clinton County, Iowa, United States. The population was 389 at the 2020 census. Charlotte was platted in 1871; a post off…Charlotte is a city in Clinton County, Iowa, United States. The population was 389 at the 2020 census. Charlotte was platted in 1871; a post office already been established there in 1853. The town was named for the first postmaster's wife, Charlotte Gilmore.